Soybean Isoflavone

1. Soy isoflavone: The multipurpose phytochemical (Review) - PMC - NCBI

  • Jun 3, 2013 · Soy isoflavones are compounds found in soybean and soybean products. They have been reported to possess numerous physiological properties, ...

  • Soy isoflavones are compounds found in soybean and soybean products. They have been reported to possess numerous physiological properties, such as antitumor, anti-menopausal (female) osteoporosis and anti-aging. They have also been reported to ...

2. Soy Isoflavones | Linus Pauling Institute | Oregon State University

  • Soy isoflavones are known to have weak estrogenic or hormone-like activity due to their structural similarity with 17-β-estradiol.

  • Contents Summary Introduction Metabolism and Bioavailability Biological Activities Estrogenic and anti-estrogenic Estrogen receptor-independent Disease Prevention Hormone-associated ca

3. Scientific Evidence Supporting the Beneficial Effects of Isoflavones on ...

  • Dec 17, 2020 · The authors reported that isoflavone intake from soy products and legumes was associated with a 19% reduction in endometrial cancer risk.

  • Isoflavones are phenolic compounds with a chemical structure similar to that of estradiol. They are present in several vegetables, mainly in legumes such as soy, white and red clover, alfalfa and beans. The most significant food source of ...

4. Benefits and Risks of Taking Isoflavones - Verywell Health

  • Sep 28, 2024 · Isoflavones are plant-based compounds primarily found in soybeans that mimic the action of the hormone estrogen. Foods rich in isoflavones ...

  • Learn about the benefits and risks of taking isoflavones for menopausal symptoms, lowering the risk of cancer and osteoporosis, and cardiovascular health.

5. Definition of soy isoflavones - NCI Drug Dictionary

6. [PDF] USDA Database for the Isoflavone Content of Selected Foods Release ...

  • Since soybeans are a major source of dietary isoflavones and soybeans and soybean products are also a good source of protein, inclusion of soy foods in the diet ...

7. Effects of soybean isoflavone aglycone on osteoporosis in ...

  • Jun 4, 2023 · Some studies have confirmed that soybean isoflavone has estrogenic activity, and the main active component of soybean isoflavones is isoflavone ...

  • Postmenopausal osteoporosis is one of the most common metabolic diseases in old women, and supplementing estrogen through bioactive substances is one of the ...

8. Increase of isoflavones in the aglycone form in soybeans ... - Nature

  • Jul 17, 2019 · Isoflavones are naturally occurring group of phytoestrogens. They are mostly found among the members of the Fabaceae family, primarily soybeans ...

  • Isoflavones are a group of phytoestrogens, naturally-occurring substances important for their role in human health. Legumes, particularly soybeans (Glycine max (L.) Merr.), are the richest source of isoflavones in human diet. Since there is not much current data on genetics of isoflavones in soybean, particularly in the aglycone form, elucidation of the mode of inheritance is necessary in order to design an efficient breeding strategy for the development of high-isoflavone soybean genotypes. Based on the isoflavone content in 23 samples of soybeans from four different maturity groups (00, 0, I and II), three crosses were made in order to determine the inheritance pattern and increase the content of total isoflavones and their aglycone form. Genotype with the lowest total isoflavone content (NS-L-146) was crossed with the low- (NS Zenit), medium (NS Maximus), and high- (NS Virtus) isoflavone genotypes. There were no significant differences in the total isoflavone content (TIF) between F2 populations, and there was no transgression among genotypes within the populations. Each genotype within all three populations had a higher TIF value than the lower parent (NS-L-146), while genotypes with a higher TIF value than the better parent were found only in the NS-L-146 × NS Zenit cross. However, significant differences in the aglycone ratio (ratio of aglycone to glycone form of isoflavones) were found between the populations. The highest aglycone ratio was found in the NS-L-146 × NS M...

9. Selective Effects of Genistein, a Soybean Isoflavone, on B ...

  • These results indicate that genistein exhibits estrogenic action in bone and bone marrow, to regulate B-lymphopoiesis and prevent bone loss.

  • Abstract. Genistein, an isoflavone abundantly present in soybeans, has structural similarity to estrogen, suggesting that genistein may act as a phytoestro

10. Current Perspectives on the Beneficial Effects of Soybean Isoflavones and ...

  • They have been known to prevent and treat various diseases, including cardiovascular diseases, metabolic syndromes, osteoporosis, diabetes, brain-related ...

  • Soybeans are rich in proteins and lipids and have become a staple part of the human diet. Besides their nutritional excellence, they have also been shown to contain various functional components, including isoflavones, and have consequently received increasing attention as a functional food item. Isoflavones are structurally similar to 17-β-estradiol and bind to estrogen receptors (ERα and ERβ). The estrogenic activity of isoflavones ranges from a hundredth to a thousandth of that of estrogen itself. Isoflavones play a role in regulating the effects of estrogen in the human body, depending on the situation. Thus, when estrogen is insufficient, isoflavones perform the functions of estrogen, and when estrogen is excessive, isoflavones block the estrogen receptors to which estrogen binds, thus acting as an estrogen antagonist. In particular, estrogen antagonistic activity is important in the breast, endometrium, and prostate, and such antagonistic activity suppresses cancer occurrence. Genistein, an isoflavone, has cancer-suppressing effects on estrogen receptor-positive (ER+) cancers, including breast cancer. It suppresses the function of enzymes such as tyrosine protein kinase, mitogen-activated kinase, and DNA polymerase II, thus inhibiting cell proliferation and inducing apoptosis. Genistein is the most biologically active and potent isoflavone candidate for cancer prevention. Furthermore, among the various physiological functions of isoflavones, they are best known for thei...

11. Isoflavones: What They Are, Benefits, and Risks - ZOE

  • Mar 19, 2024 · Summary. Isoflavones are a type of polyphenol found in soy and soy products. Including isoflavones and other phytoestrogens in your diet may ...

  • What are isoflavones and should you be eating them? This article explains the benefits, risks, and ways to include them in your diet.

12. Soy Isoflavones Oral: Uses, Side Effects, Interactions ... - WebMD

  • Uses. Soy has been used to treat certain symptoms of menopause (such as hot flashes) and to help prevent bone loss (osteoporosis).Some supplement products have ...

  • Find patient medical information for Soy Isoflavones oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

13. Soy Isoflavones | Learn More | SNI Institute

  • Isoflavones have been purported to exert several health benefits, from reducing cancer risk 5,6 to alleviating menopausal symptoms 7 and improving memory.

  • Learn about the health effects of Soy Isoflavones here. Soy can be a beneficial (and delicious) addition to your health and lifestyle.

14. Straight Talk About Soy - The Nutrition Source

  • Soy is a unique food that is widely studied for its estrogenic and anti-estrogenic effects on the body.

  • The Takeaway: Soy is a unique food that is widely studied for its estrogenic and anti-estrogenic effects on the body. Studies may seem to present conflicting conclusions about soy, but this is larg…

15. Soybeans and soy foods - Better Health Channel

  • The soybean may be a superfood that can reduce the risk of a range of health problems.

16. Soybean isoflavones potentially prevent sarcopenia: a systematic ...

  • Dec 8, 2023 · The present study showed the potential of soy isoflavones as a preventer of sarcopenia by preventing muscle loss.

  • Soybean is an important food resource that has been used for centuries in Korean cuisine. Soybean is considered a good source of protein and a nutritional powerhouse. Isoflavone, one of the components of soybean, has been investigated for its nutritional role and physiological effects. As soybean can supply sufficient proteins for muscle and soybean isoflavone might have a direct effect on muscle, soybean could be a potential nutritional treatment for muscle atrophy. However, the effect of isoflavone on muscle atrophy is controversial. Four in vitro studies and four in vivo studies were selected from the literature to determine the potential capacity of isoflavones as preventers of sarcopenia. In vitro and in vivo studies, there have been studies that isoflavone extracted from soybean is effective in preventing muscle atrophy. Research on soybean isoflavone and muscle loss included in this study showed that soybean isoflavone may prevent myotube atrophy by blocking the expression of MuRF1 or by regulating androgen receptors. Isoflavone has been shown to increase the diameter of myoblasts and increase muscle mass. The present study showed the potential of soy isoflavones as a preventer of sarcopenia by preventing muscle loss.

17. SOY: Overview, Uses, Side Effects, Precautions, Interactions ... - WebMD

  • Soy is used for high cholesterol, high blood pressure, heart disease, diabetes, symptoms of menopause, and premenstrual syndrome (PMS).

  • Learn more about SOY uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain SOY.

18. Enrichment of Polyglucosylated Isoflavones from Soybean ... - MDPI

  • Isoflavones in soybeans are well-known phytoestrogens. Soy isoflavones present in conjugated forms are converted to aglycone forms during processing and ...

  • Isoflavones in soybeans are well-known phytoestrogens. Soy isoflavones present in conjugated forms are converted to aglycone forms during processing and storage. Isoflavone aglycones (IFAs) of soybeans in human diets have poor solubility in water, resulting in low bioavailability and bioactivity. Enzyme-mediated glycosylation is an efficient and environmentally friendly way to modify the physicochemical properties of soy IFAs. In this study, we determined the optimal reaction conditions for Deinococcus geothermalis amylosucrase-mediated α-1,4 glycosylation of IFA-rich soybean extract to improve the bioaccessibility of IFAs. The conversion yields of soy IFAs were in decreasing order as follows: genistein > daidzein > glycitein. An enzyme quantity of 5 U and donor:acceptor ratios of 1000:1 (glycitein) and 400:1 (daidzein and genistein) resulted in high conversion yield (average 95.7%). These optimal reaction conditions for transglycosylation can be used to obtain transglycosylated IFA-rich functional ingredients from soybeans.

19. Soy Information | Mount Sinai - New York

  • Studies suggest that soy protein may reduce the risk of heart disease by lowering levels of LDL (bad) cholesterol.

  • Learn about Soy or find a doctor at Mount Sinai Health System.

20. Isoflavone: Uses, Interactions, Mechanism of Action - DrugBank

  • Oct 20, 2016 · Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram. The main soy isoflavones ...

  • Isoflavone is a biologically active phytoestrogen found in high concentrations in soy and other legumes.

21. Isoflavone (Aglycon) Mixture, from Soybean - FUJIFILM Wako

  • [Isoflavone (Aglycon) Mixture, from Soybean] .We manufacture and distribute chemical reagents for research use only or various antibodies.

Soybean Isoflavone
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